- Case Report
- Nephrology (Genitourinary)
- Successful treatment of tubulointerstitial nephritis and uveitis with steroid and azathioprine in a 12-year-old boy
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Ji Eun Kim, Se Jin Park, Ji Young Oh, Hyeon Joo Jeong, Ji Hong Kim, Jae Il Shin
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Clin Exp Pediatr. 2016;59(Suppl 1):S99-S102. Published online November 30, 2016
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Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease, often underdiagnosed or misdiagnosed in children. We describe the case of a 12-year-old boy who presented to Severance Hospital with a 1-month history of bilateral conjunctival injection. He was first evaluated by an Ophthalmologist in another hospital and diagnosed with panuveitis. Laboratory tests indicated renal failure, and a renal biopsy... |
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- Review Article
- Nephrology (Genitourinary)
- Pathogenesis of minimal change nephrotic syndrome: an immunological concept
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Seong Heon Kim, Se Jin Park, Kyoung Hee Han, Andreas Kronbichler, Moin A. Saleem, Jun Oh, Beom Jin Lim, Jae Il Shin
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Clin Exp Pediatr. 2016;59(5):205-211. Published online May 31, 2016
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Idiopathic nephrotic syndrome (INS) in children is characterized by massive proteinuria and hypoalbuminemia. Minimal change nephrotic syndrome (MCNS) is the most common form of INS in children. The pathogenesis of MCNS still remains unclear, however, several hypotheses have been recently proposed. For several decades, MCNS has been considered a T-cell disorder, which causes the impairment of the glomerular filtration barrier... |
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- Original Article
- Nephrology (Genitourinary)
- Usefulness of neutrophil-lymphocyte ratio in young children with febrile urinary tract infection
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Song Yi Han, I Re Lee, Se Jin Park, Ji Hong Kim, Jae Il Shin
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Clin Exp Pediatr. 2016;59(3):139-144. Published online March 31, 2016
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Purpose Acute pyelonephritis (APN) is a serious bacterial infection that can cause renal scarring in children. Early identification of APN is critical to improve treatment outcomes. The neutrophil-lymphocyte ratio (NLR) is a prognostic marker of many diseases, but it has not yet been established in urinary tract infection (UTI). The aim of this study was to determine whether NLR is a... |
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- Review Article
- Inflammation and hyponatremia: an underrecognized condition?
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Se Jin Park, Jae Il Shin
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Clin Exp Pediatr. 2013;56(12):519-522. Published online December 20, 2013
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Timely diagnosis of hyponatremia is important for preventing potential morbidity and mortality as it is often an indicator of underlying disease. The most common cause of eurvolemic hyponatremia is the syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Recent studies have demonstrated that proinflammatory cytokines such as interleukin (IL) 1β and IL-6 are involved in the development of hyponatremia, a condition... |
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- Case Report
- Urinary bladder rupture during voiding cystourethrography
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Kyong Ok Lee, Se Jin Park, Jae Il Shin, Suk Young Lee, Kee Hyuck Kim
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Clin Exp Pediatr. 2012;55(5):181-184. Published online May 21, 2012
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Voiding cystourethrography (VCUG) is a commonly performed diagnostic procedure for the evaluation of vesicoureteral reflux with urinary tract infection or congenital renal diseases in children. The procedure is relatively simple and cost-effective, and complications are very rare. The iatrogenic complication of VCUG range from discomfort, urinary tract infection to bacteremia, as well as bladder rupture. Bladder rupture is a rare... |
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- Review Article
- Complications of nephrotic syndrome
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Se Jin Park, Jae Il Shin
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Clin Exp Pediatr. 2011;54(8):322-328. Published online August 31, 2011
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Nephrotic syndrome (NS) is one of the most common glomerular diseases that affect children. Renal histology reveals the presence of minimal change nephrotic syndrome (MCNS) in more than 80% of these patients. Most patients with MCNS have favorable outcomes without complications. However, a few of these children have lesions of focal segmental glomerulosclerosis, suffer from severe and prolonged proteinuria, and... |
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- Original Article
- Discordant findings on dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritis
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Jeongmin Lee, Duck Geun Kwon, Se Jin Park, Ki-Soo Pai
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Clin Exp Pediatr. 2011;54(5):212-218. Published online May 31, 2011
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Purpose The diagnosis of acute pyelonephritis (APN) is often difficult, as its clinical and biological manifestations are non-specific in children. If not treated quickly and adequately, however, APN may cause irreversible renal damage, possibly leading to hypertension and chronic renal failure. We were suspecting the diagnostic value of 99mTc-dimercaptosuccinic acid (DMSA) scan by experiences and so compared the results of DMSA... |
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- Kikuchi-Fujimoto disease with aseptic meningitis
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Se Jin Park, Won Jin Moon, Wan Seop Kim, Kyo Sun Kim
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Clin Exp Pediatr. 2009;52(5):622-626. Published online May 15, 2009
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Kikuchi-Fujimoto disease was initially described as a self-limiting histiocytic necrotizing lymphadenitis in Japan in 1972, and is predominantly observed in women under the age of 30 year and in Asian populations. The pathogenesis is still poorly understood but is thought to include infections, and autoimmune and neoplastic diseases. The most common clinical manifestations are fever and painless cervical lymphadenitis. Diagnosis... |
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- Original Article
- Risk Factors for Cardiovascular Disease in Obese Children
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Su Jin Cho, Se Jin Park, Il Tae Hwang, Young Mi Hong
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Clin Exp Pediatr. 2001;44(5):493-500. Published online May 15, 2001
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Purpose : Obesity is known to be associated with complications such as hypertension, dyslipidemia, and insulin resistance. The importance of insulin resistance and hyperinsulinemia have been emphasized in obesity. Homocysteine is an emerging important risk factor for cardiovascular disease in adult, but there are less reports about homocysteine in children. Several risk factors such as blood pressure, lipid profiles, serum... |
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- Relationship between Serum Leptin Levels and
Other Predictors in Obese Children
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Se Jin Park, Ki Won Park, Young Mi Hong
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Clin Exp Pediatr. 2001;44(10):1103-1111. Published online October 15, 2001
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Purpose : The product of the ob gene, leptin is an adipocyte specific hormone that might be involved in the regulation of food intake by the central neuroendocrine system. Recent studies reported that serum leptin concentrations were correlated with Body mass index(BMI) and other obesity measurements. The aims of this study were to evaluate leptin concentrations according to degree of... |
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